Danish 82c trial

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WebMay 1, 2024 · A 30-year long-term report from the Danish breast cancer cooperative group DBCG 82bc trial ... Danish Breast Cancer Cooperative Group DBCG 82c randomised … WebOct 2, 1997 · Background: Irradiation after mastectomy can reduce locoregional recurrences in women with breast cancer, but whether it prolongs survival remains controversial. We …

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WebJun 11, 2024 · An increase in the actuarial risk of ischemic heart disease was not seen in the analysis of the Danish Breast Cancer Group trials 82b and 82c, in which more than 3,000 patients were followed (5) . These data have led Kurtz to note the potential hazard of thoracic irradiation and to highlight the importance of radiotherapy technique in breast ... WebDec 12, 2024 · Based on results from the Danish Breast Cancer Cooperative Group 82b and 82c trials, which demonstrated a survival … fischer comfort cruiser mounted

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WebIn Postmenopausal Danish Trial 82c, as in Premenopausal Danish Trial 82b, inadequate surgical Tx of the axilla resulted in a median of only 7 axillary LNs removed at surgery. A suboptimal duration of tamoxifen was also employed (1 yr vs. the typical 5 yrs). WebJul 2, 2024 · In this trial, 318 premenopausal women with high-risk breast cancer were randomized to mastectomy and chemotherapy or chemotherapy plus RT. Patients in the radiation arm exhibited a reduction in 10-year LRR, as in the DBCCG trials. The Danish 82c trial studied the effect of PMRT in high-risk postmenopausal women using a similar … WebStudy with Quizlet and memorize flashcards containing terms like Lifetime Risk of breast cancer, EIC definition, NSABP B-04 arms and more. camping rolf köln

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WebDanish 82b trial: premenopausal, high-risk. Danish 82c trial: postmenopausal, high-risk. Vancouver BC: premenopausal, LN+. All 3 trials found better PMRT improved local-All 3 trials found better PMRT improved localregional. … WebMay 15, 1999 · Postoperative radiotherapy decreased the risk of locoregional recurrence and was associated with improved survival in high-risk postmenopausal breast-cancer … fischercompany.comWebFeb 9, 2009 · The Danish 82c study assessing PMRT in postmenopausal women receiving one year adjuvant tamoxifen also revealed similar reductions in LRF (8% v. 35%, p < 0.001) and improved 10 year overall survival (45% v. 36%, p = 0.03) . There are a number of reasons why a survival advantage may not have initially been apparent. fischercommunitybiblestudy.org

"WebSep 11, 2013 · The Danish group also undertook a study in high risk postmenopausal patients. Specifically, in the Danish 82c trial randomized 1460 postmenopausal patients younger than 70 years of age after total mastectomy and axillary dissection, to postmastectomy radiation therapy in addition to tamoxifen for one year or tamoxifen alone . " - Danish 82c trial

Danish 82c trial

Postoperative radiotherapy in high-risk postmenopausal

WebThe Danish 82c trial randomized 1,375 high-risk postmenopausal women who underwent total mastectomy with partial axillary node dissection to tamoxifen alone or tamoxifen …

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WebApr 17, 2010 · A subgroup analysis of the Danish 82b and 82c trials suggests that the proportional survival benefit from improved local control actually varies among women … WebMay 8, 2014 · The Danish 82b trial demonstrated the use of PMRT, in conjunction with systemic chemotherapy, reduced local failure (LF) by 23 % and improved diseasefree survival (DFS) and OS by 14 % and 9 %, respectively. 7 In the Danish 82c trial the use of PMRT, in addition to hormonal therapy, reduced LF by 27 % and improved OS by 9 %.8 …

WebApr 13, 2004 · As well, in the Danish 82c trial, 1 year of tamoxifen therapy was used, as opposed to the current standard of 5 years of tamoxifen therapy. In the Danish 82b trial and the British Columbia trial, CMF chemotherapy was used,5, 6 as opposed to anthracycline chemotherapy currently in common use.42 WebAug 1, 2006 · (1999) Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. Lancet 353: 1641–1648

WebNov 24, 2010 · The Danish 82c trial randomized 1375 postmenopausal high-risk breast cancer patients younger than 70 years of age, status post total mastectomy and axillary dissection, to radiation therapy plus tamoxifen vs. tamoxifen alone . WebApr 1, 2010 · In a subsequent analysis of the 82b and 82c trials no increase in cardiac morbidity was seen in the irradiated arm. 14 The Danish 82b trial was criticised for the suboptimal intensity of chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil (CMF) 15 and inadequate axillary surgery with only a median of 7 nodes …

WebJan 12, 2024 · NSABP-B06 (1976–1980) 25-Year follow-up of a randomized trial of 590, 632, and 629 patients treated with mastectomy, lumpectomy alone, or lumpectomy followed by adjuvant RT Cumulative incidence of …

WebThe role of postmastectomy irradiation together with systemic treatment was evaluated in high-risk patients included in the Danish Breast Cancer Cooperative Group (DBCG) protocol 82. As of June 1989, a total of 1473 pre- and menopausal patients were randomized to postmastectomy irradiation + CMF ver … fischer commodities llcWebTrial Oversight. The Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality (DANISH) was an investigator-initiated multicenter, randomized ... fischer communicationsWebAug 28, 2016 · Principal Findings: The primary outcome, incidence of all-cause mortality, occurred in 21.6% of the ICD group versus 23.4% of the control group (p = 0.28). Younger patients (<59 years) appeared to derive greater benefit from ICD implantation versus older patients (p for interaction = 0.009). Sudden cardiac death: 4.3% versus 8.2%; … fischer commercial flooring billings mtWebBetween 1982 and 1990, postmenopausal women with high-risk breast cancer (stage II or III) were randomly assigned adjuvant tamoxifen (30 mg daily for 1 year) alone (689) or … camping rolf köln wohnwagenWebDec 9, 2024 · During a median follow-up of 9.5 years (compared with 5.6 years in the original DANISH trial), ICD implantation did not provide an overall long-term survival benefit. However, patients ≤70 years in the … fischer comicWebMay 10, 2013 · Danish Breast Cancer Cooperative Group 82b Trial. N Engl J Med. 1997;337(14):949-955. ... Danish Breast Cancer Cooperative Group DBCG 82c Trial. ... camping roland buchenWebMay 15, 1999 · Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. Author links open overlay panel Dr Marie Overgaard MD a, Maj-Britt Jensen MSc c, Jens Overgaard MD b, Per S Hansen MD f, ... camping roll mat argos