site stats

Slc25a11 neuron

WebKnockdown of the Slc25a11 gene in immortalized mouse chromaffin cells resulted in a hypermethylated and pseudohypoxic phenotype, and the cells showed increased adhesion and migration compared to controls, suggesting the acquisition of metastatic properties. These defects could be rescued by wildtype Slc25a11. WebFeb 10, 2012 · The 2-oxoglutarate carrier (SLC25A11) exchanges the oxo-dicarboxylic acid for malate as an electroneutral exchange of dianionic species. Together with the electrogenic glutamate–aspartate transporter, the 2-oxoglutarate transporter is a component of the malate–aspartate shuttle.

Entry - #618464 - PARAGANGLIOMAS 6; PGL6 - OMIM

WebOct 27, 2024 · Fig. 2: SLC25A39 is required for mitochondrial GSH import. a, Volcano plot showing the log 2 fold change in mitochondrial metabolite abundance versus −log P values from SLC25A39 -knockout HeLa ... WebThe SLC25 Mitochondrial Carrier Family: Structure and Mechanism Members of the mitochondrial carrier family (SLC25) provide the transport steps for amino acids, … how to work out boiling point https://quingmail.com

The SLC25 Mitochondrial Carrier Family: Structure and

WebMetabolite analysis of SLC25A11 knockdown cancer cells revealed that the MAS is responsible for ATP production in cancer cells. (a, b) Targeted LC-MS/MS metabolite analysis in UACC62 (a) and A549 ... WebNational Center for Biotechnology Information WebJan 25, 2024 · We have proposed that the oxoglutarate carrier SLC25A11 is important for ATP production in cancer by NADH transportation from the cytosol to mitochondria as a … how to work out body composition

SLC25A12 expression is associated with neurite outgrowth

Category:SLC25A12 expression is associated with neurite outgrowth

Tags:Slc25a11 neuron

Slc25a11 neuron

Mitochondrial outer membrane protein FUNDC2 …

WebMembers of the mitochondrial carrier family (SLC25) provide the transport steps for amino acids, carboxylic acids, fatty acids, cofactors, inorganic ions, and nucleotides across the mitochondrial inner membrane and are crucial for many cellular processes. Here, we use new insights into the transport mechanism of the mitochondrial ADP/ATP carrier to … WebSLC25A11 is localized in the mitochondrial inner membrane, serving as a mitochondrial GSH transporter to import GSH into mitochondria. Coimmunoprecipitation (Co-IP) analysis revealed that FUNDC2 …

Slc25a11 neuron

Did you know?

WebDec 1, 2024 · The meaning of mitochondrial movement to a neuron's life. Biochim. Biophys. Acta (2013) G. Lopez-Domenech et al. ... We have proposed that the oxoglutarate carrier SLC25A11 is important for ATP production in cancer by NADH transportation from the cytosol to mitochondria as a malate. We have examined not only changes of ATP and … WebSep 23, 2015 · To generate new insights into the biology of Alzheimer’s Disease (AD), we developed methods to combine and reuse a wide variety of existing data sets in new ways. We first identified genes ...

WebDec 11, 2024 · Under repeated agonistic interactions expression of at least 7 of these genes—the Slc25a5, Slc25a11, Slc25a28, Slc2538, ... psychosis, and motor neuron disease. A mutation in the Slc25a19 gene was found to be associated with Amish microcephaly, neuropathy and bilateral striatal necrosis. The Slc25a29 gene codes for a … WebJan 25, 2024 · We have proposed that the oxoglutarate carrier SLC25A11 is important for ATP production in cancer by NADH transportation from the cytosol to mitochondria as a malate. We have examined not only changes of ATP and NADH but also changes of metabolites after SLC25A11 knock down in cancer cells. Findings

WebSLC25A11. METABOLIC PATHWAYS. Human metabolism. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. WebMar 5, 2024 · SLC25A11. solute carrier family 25 member 11. Gene ID: 8402, updated on 5-Mar-2024. Gene type: protein coding. Also known as: OGC; PGL6; SLC20A4. See all …

WebNX_Q02978 - SLC25A11 - Mitochondrial 2-oxoglutarate/malate carrier protein - Function. Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the ...

WebSLC25A11 Antibody (E-2) is a mouse monoclonal IgG 1 κ SLC25A11 antibody, cited in 4 publications, provided at 200 µg/ml. specific for an epitope mapping between amino acids 142-159 within an internal region of SLC25A11 of human origin. SLC25A11 Antibody (E-2) is recommended for detection of SLC25A11 of mouse, rat and human origin by WB, IP ... how to work out boiler size for houseWebFeb 25, 2024 · SLC25A1 neuron transgenic mice display differential changes in the proteome and acetyl-proteome. To resolve the potential molecular mechanisms of the … origin ordinaryhow to work out body surface areaWebMar 1, 2024 · Members of the mitochondrial carrier family (SLC25) provide the transport steps for amino acids, carboxylic acids, fatty acids, cofactors, inorganic ions, and … how to work out bonferroni correctionWebMar 1, 2024 · The Mitochondrial Carrier Family. With 53 members, the mitochondrial carrier family (solute carrier family 25, SLC25) is the largest solute transporter family in humans. They transport solutes across the impermeable inner membrane of mitochondria for important cellular processes, such as oxidative phosphorylation of fats and sugars, … how to work out bonus percentageWebNov 1, 2014 · Citrate shuttling in astrocytes is required for processing cocaine-induced neuron-derived excess peroxidated fatty acids. 2024, iScience. ... Furthermore, in silico analysis revealed that overexpression of SLC25A10 but not SLC25A11 is associated with reduced overall survival in lung- and breast-cancer patients. how to work out bowling averagesWebdata show that SLC25A11 is a novel paraganglioma susceptibility gene for which loss of function correlates with metastatic presentation. Cancer cells critically depended on the … how to work out bounds maths